27 August: PILA PHARMA AB (publ) (FN STO: PILA), a clinical stage biotech company pioneering development of an oral TRPV1-antagonist as a potential first-in-class treatment for obesity and diabetes, today published the Company’s interim report for the period January – June 2026. The interim report can be found on the Company’s website: https://pilapharma.com/financial-reports/

27 August: PILA PHARMA AB (publ) (FN STO: PILA), a clinical stage biotech company pioneering development of an oral TRPV1-antagonist as a potential first-in-class treatment for obesity and diabetes, today published the Company’s interim report for the period January – June 2026. The interim report can be found on the Company’s website: https://pilapharma.com/financial-reports/

The Company invites shareholders or other interested parties to attend an online live interview with Q&A, hosted together with Direkt Studios. The CEO Gustav H. Gram will discuss the report, the key happenings for PILA PHARMA in the first half of 2026, and tune in on the forward-coming milestones and events.

PILA PHARMA recently received the regulatory approval to conduct PP-CT04. The trial seeks to explore a within-subject dose titration approach to reach anticipated therapeutic plasma concentrations of XEN-D0501 not previously investigated. The trial will be carried out in people living with obesity.

Dose escalation will be carried out individually for each participant, beginning at 4 mg bi-daily and increasing stepwise up to a maximum of 16 mg bi-daily. Each dose level will be administered for 1 week, resulting in a maximum dose escalation period of 4 weeks. Once the highest tolerable dose has been reached and confirmed to be tolerable, the participant will continue treatment at that dose for an 8-week maintenance period.

Importantly, in PILA PHARMA's last clinical trial (PP-CT02) in people living with obesity and diabetes where good safety and signs of efficacy were shown, only 4mg was administered bi-daily for 4 weeks. It is therefore a substantial step forward to assess potentially much higher doses and longer durations, something believed is needed to achieve the best results.

Link to the event can be found here: https://www.youtube.com/live/FjVmquk8zq0?si=qFrjyYhCQcljArVR

For more information:Gustav H. Gram, CEOghg@pilapharma.com

PILA PHARMA’s share ticker PILA is subject to trade on Nasdaq First North Growth Market, Sweden with Aqurat Fondkommission AB as Certified Adviser. Contact: M: ca@aqurat.se - T: +46 (0)8 684 05 800

About PILA PHARMA AB (Publ)PILA PHARMA AB is a Swedish clinical stage biotech company based in Malmö, Sweden. The aim of the company is to develop TRPV1 antagonists as a novel treatment of obesity and diabetes. The Company owns a TRPV1 asset with data and chemical entities including the clinical development candidate XEN-D0501. In July 2022, the Company was moreover awarded orphan drug designation ("ODD") for XEN-D0501 as a treatment for the painful rare disease erythromelalgia.

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AttachmentsPILA PHARMA: INVITATION TO H1 REPORT REVIEW WITH Q&A, TODAY 27 AUGUST AT 11:00 CET